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Academic Article
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Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants.
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Academic Article
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Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study.
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Academic Article
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Longitudinal association of PCSK9 sequence variations with low-density lipoprotein cholesterol levels: the Coronary Artery Risk Development in Young Adults Study.
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Academic Article
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Ethnic and sex differences in the prevalence, treatment, and control of dyslipidemia among hypertensive adults in the GENOA study.
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Academic Article
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Biological, clinical and population relevance of 95 loci for blood lipids.
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Academic Article
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The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study.
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Academic Article
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Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships.
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Academic Article
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Pharmacogenetics of response to statins: where do we stand?
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Academic Article
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Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study.
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Academic Article
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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
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Academic Article
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Atypical angiopoietin-like protein that regulates ANGPTL3.
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Academic Article
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Relation of PCSK9 mutations to serum low-density lipoprotein cholesterol in childhood and adulthood (from The Bogalusa Heart Study).
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Academic Article
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Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence.
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Academic Article
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Low-density lipoprotein and high-density lipoprotein cholesterol levels in relation to genetic polymorphisms and menopausal status: the Atherosclerosis Risk in Communities (ARIC) Study.
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Academic Article
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APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels.
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Academic Article
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HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study.
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Academic Article
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Admixture mapping of quantitative trait loci for blood lipids in African-Americans.
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Academic Article
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Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study.
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Academic Article
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Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study.
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Academic Article
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Candidate gene association resource (CARe): design, methods, and proof of concept.
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Academic Article
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Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study.
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Academic Article
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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
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Academic Article
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Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
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Academic Article
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Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations.
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Academic Article
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Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study.
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Academic Article
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Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.
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Academic Article
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SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study.
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Academic Article
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Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
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Academic Article
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Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease.
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Academic Article
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Risk factor correlates of platelet and leukocyte markers assessed by flow cytometry in a population-based sample.
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Academic Article
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Effects of apolipoprotein E genotype on blood cholesterol in adolescent girls.
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Academic Article
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Correlates of carotid plaque presence and composition as measured by MRI: the Atherosclerosis Risk in Communities Study.
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Academic Article
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Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study.
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Academic Article
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Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
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Concept
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Cholesterol, LDL
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Academic Article
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Common variants associated with plasma triglycerides and risk for coronary artery disease.
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Academic Article
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Discovery and refinement of loci associated with lipid levels.
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Academic Article
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Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study.
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Academic Article
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Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
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Academic Article
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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
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Academic Article
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Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program.
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Academic Article
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Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
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Academic Article
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Inactivating mutations in NPC1L1 and protection from coronary heart disease.
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Academic Article
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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
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Academic Article
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Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families.
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Academic Article
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Directional dominance on stature and cognition in?diverse human populations.
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Academic Article
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Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia.
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Academic Article
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Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.
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Academic Article
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Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities).
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Academic Article
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Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits.
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Academic Article
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Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos.
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Academic Article
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Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease.
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Academic Article
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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
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Grant
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EPIDEMIOLOGY OF GENETIC FACTORS IN LIPID METABOLISM
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Academic Article
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Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
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Academic Article
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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
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Academic Article
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Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study.
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Academic Article
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Whole genome sequence analysis of blood lipid levels in >66,000 individuals.
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Academic Article
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Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease.
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Academic Article
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Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk.
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Academic Article
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Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol.
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